Research Opportunity

Dr. Shashank Sirsi (lab alumnus, and now Assistant Professor of BME at UT Dallas) is looking for enthusiastic research assistants and graduate students to start immediately.  Dr. Sirsi is an outstanding young investigator with very innovative ideas, and the new UT Dallas/Southwestern MC group (including Dr. Robert Mattrey and Dr. Kenneth Hoyt) and is set to become a center of excellence in ultrasound imaging and theranostics.  Please contact Dr. Sirsi directly at:

shashank.sirsi@utdallas.edu

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New Biomaterials Paper

Congratulations to the Ulster and Oxford team for yet another excellent oxygen sonodynamic therapy paper:

http://www.sciencedirect.com/science/article/pii/S0142961215009370

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New Sonoporation Paper

Congratulations to Kang-Ho Song and Alex Fan, as well as our collaborators at UCCS and AMC on this publication in Theranostics.

http://www.thno.org/v05p1419.htm

We developed a novel high-throughput sonoporation device.  The study shows the effect of microbubble size on in vitro cell sonoporation, death and lysis, and the use of sequential sonoporations to improve efficiency beyond the prior 50% limit.

KHS sonoporation device

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New paper on nanodrops for sonothermetry

Congrats to Paul Mountford and Will Smith on the new article in Langmuir!

Mountford Langmuir 2015 thermal probes

This article examines superheated fluorocarbon mixtures for acoustic droplet vaporization.  Effects of chemical composition, temperature and mechanical index are measured.  The mixtures work great to tune the vaporization temperature in closed systems, but not so well in open systems.  Nevertheless, the concept of using superheated fluorocarbons for imaging temperature thresholds is shown.  The paper also includes a new model on superheated droplet dissolution:

http://pubs.acs.org/articlesonrequest/AOR-sbTgB7AI2MS2GN5Dfeva

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Open position for engineer

Professional Research Associate (PRA):

The Borden Lab at the University of Colorado Boulder is currently looking to hire an engineer to work in the university laboratory on process scale-up.  The work will involve design, fabrication and testing of an emulsion synthesis process to increase capacity by an order of magnitude.  Qualifications include a BS or MS in Biomedical Engineering, Chemical Engineering or Mechanical Engineering.

Applicants should contact Prof. Mark Borden by email: mark.borden@colorado.edu

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Congrats to Dr Mountford

Congratulations to Paul Mountford for successfully defending his PhD:

Molecular Thermodynamics of Superheated Lipid-Coated Fluorocarbon Nanoemulsions

image

Here’s a picture of the celebration at the bike park in Crested Butte:

image

Left to right: Paul Dayton, Will Smith, Mark Borden, Paul Mountford

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New NIH R21 grant

Together with Ben Terry at UNL and Keely Buesing at UNMC, we will investigate peritoneal microbubble oxygenation to treat acute respiratory distress syndrome (ARDS).

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New Oxygen Delivery Paper

We published a new paper on peritoneal microbubble oxygenation with Ben Terry’s group at UNL.

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Talk at ACS Colloids

Prof. Borden will be presenting on “Design Rules for Acoustic Phase Change Agents” at the 89th ACS Colloids meeting next week in Pittsburgh, PA.

http://www.colloids2015.org/Colloids2015/Home.html

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Mechanical Engineering Hero: JW Gibbs

JWGibbs

Josiah Willard Gibbs (1839-1903): “an American scientist who made important theoretical contributions to physics, chemistry, and mathematics. His work on the applications of thermodynamics was instrumental in transforming physical chemistry into a rigorous deductive science.”

He earned the first American PhD in engineering; his dissertation was entitled “On the Form of the Teeth of Wheels in Spur Gearing”…that’s right folks, classical component design!

Einstein called him: “the greatest mind in American history”

Among his many contributions: chemical thermodynamics, statistical mechanics, vector calculus and physical optics.

So, don’t ever let anyone tell you that mechanical engineers don’t do chemistry!

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